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CD14 anticorps (AA 65-327)

Cet anticorps Lapin Polyclonal détecte spécifiquement CD14 dans WB et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.
N° du produit ABIN4950462

Aperçu rapide pour CD14 anticorps (AA 65-327) (ABIN4950462)

Antigène

Voir toutes CD14 Anticorps
CD14

Reactivité

  • 302
  • 59
  • 38
  • 26
  • 23
  • 22
  • 22
  • 22
  • 19
  • 18
  • 17
  • 14
  • 14
  • 13
  • 12
  • 9
  • 7
  • 7
  • 6
  • 4
  • 4
  • 2
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 260
  • 68
  • 38
  • 3
  • 3
  • 1
  • 1
  • 1
Lapin

Clonalité

  • 307
  • 65
  • 2
Polyclonal

Conjugué

  • 158
  • 34
  • 25
  • 21
  • 17
  • 10
  • 7
  • 6
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CD14 est non-conjugé

Application

  • 262
  • 123
  • 102
  • 69
  • 63
  • 52
  • 28
  • 24
  • 20
  • 14
  • 11
  • 7
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Épitope

    • 37
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 65-327

    Purification

    Antigen affinity

    Immunogène

    Amino acids 65-327 of human CD14 were used as the immunogen for the CD14 antibody.

    Isotype

    IgG
  • Indications d'application

    Optimal dilution of the CD14 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

    Restrictions

    For Research Use only
  • Buffer

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    Stock

    -20 °C

    Stockage commentaire

    After reconstitution, the CD14 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Antigène

    CD14

    Autre désignation

    CD14

    Sujet

    CD14 is a single-copy gene encoding 2 protein forms: a 50- to 55-kD glycosylphosphatidylinositol-anchored membrane protein (mCD14) and a monocyte or liver-derived soluble serum protein (sCD14) that lacks the anchor. This gene is located at bands 5q23-q31. The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. CD14 acts as a co-receptor (along with the Toll-like receptor TLR 4 and MD-2) for the detection of bacterial lipopolysaccharide (LPS). CD14 can bind LPS only in the presence of lipopolysaccharide-binding protein (LBP). Although LPS is considered its main ligand, CD14 also recognizes other pathogen-associated molecular patterns.

    UniProt

    P08571

    Pathways

    Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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